Date: 2006.9.22 (Fri) 15:30-16:45
Place: Building No.4, Research Center for Advanced Science and Technology
Speaker: Hiroshi Fukunari
Title: Multi-Scale and Physics Simulation of Cardiovascular System
Keywords: Cardiovascular diseases, computer simulation, dynamics of blood flow, fluid-structure interaction finite element method, finite volume method

Affiliation: Institute of Industrial Science, University of Tokyo
Position: Research Fellow
Disciplines: Biomechanics
Societies and Conferences:Japan Society Mechanical Engineering, THE JAPAN SOCIETY FOR COMPUTATIONAL ENGINEERING AND SCIENCE, World Congress of Biomechanics, Asian Pacific conference on Biomechanics

Bibliography: Hiroshi Fukunari, Multi-Scale and Physics Simulation of Cardiovascular System, Human Science Integration Seminar Abstracts, No. 20, pp. 1, 2006.

Abstract:
The three most common causes of death in Japan are cancer, Cardiac diseases and Cerebrovascular diseases.
In our laboratory, we are trying to reveal the mechanism of cardiovascular diseases from the point of dynamics of the blood circulation. Our present
targets are Cerebral Aneurysms and sclerosis of the arteries. Both of experimental research and computer simulation are utilized to tackle with them.

We also are participating a project hosted by MEXT (Ministry of Education, Culture, Sports, Science and Technology), "Revolutionary Simulation Software".
In this project, we are developing a numerical simulation software "M-SPhyR Circulation" to obtain a better understanding of the cardiovascular system in
a multi-scale and multi-physic manner such that mechanical, biochemical and physiological phenomena are dealt with in wide ranges of scales.
"M-SPhyR Circulation" is composed of three main components,
1) MC-Modeling, a 3D modeling software for Image-based modeling of blood vessels
2) MC-BFlow, a Finite Volume method analysis code for large size blood flow simulation
3) MC-DIAS, a Fluid Structure Interaction Finite Element Method Code, for analysis of blood flow and vessel walls
Other add-in codes can be added to deal with material transportations in blood flow and vessel walls and blood flows in peripheral arteries.

This research is expected to be beneficial in developing new prevention and therapeutic methods for cardiovascular diseases.
The software is an open-source code and to be released in 2007.

In this lecture, I will introduce the overview of our cardiovascular research, and its methodology and achievements so far.

References:
[1]Oshima M, "Image-based simulation of blood flow for Cerebrovascular Disorders.", Nagare, 21, 2002, pp.121-128.
[2]http://www.rss21.iis.u-tokyo.ac.jp/