2007-07-02: Human SCINT Seminar (23)
Poster Mihoko Otake Registed 2007-06-24 22:42 (1632 hits) Date: 2007.07.02 (Mon) 14:00-15:15 Place: Kashiwa Campus, General Research Building, Room 630. Speaker: Hiroyuki Tsubomi Title: Cortical mechanisms of attentional effect in vision - an fMRI study with individual difference approach - Keywords: visual attention, attentional effect, individual difference, fMRI, cortical network, structural equation modeling Affiliation: Research Center for Advanced Science and Technology, The University of Tokyo
Position: Assistant Professor Disciplines: psychology Abstract: Human cortex, a large parallel processing system, seems a capacity limited in nature. Previous behavioral studies have suggested that top-down attention biases visual information processing while its cortical mechanism remains unclear. We reviewed current cognitive neuroscience literatures on neural representation of top-down attention. Furthermore, by applying the structure equation modeling (SEM) to our recent fMRI data derived from the experiment, we found the cortical network of the top-down attention working from the frontal (dosolateral premotor cortex and frontal eye field) down to extrastriate and striate visual cortices via the right intraparietal sulcus. This top-down attentional modulation resolves stimulus competition in early visual cortices by enhancing the task-relevant visual information. References: [1] Lennie, P. (2003). The cost of cortical computation. *Current Biolology*,*13*, 493-497. [2] Desimone, R., & Duncan, J. (1995). Neural mechanisms of selective visual attention. *Annual Review of Neuroscience*, *18*, 193-222. [3] Farah, M. J. (2000).* The cognitive neuroscience of vision*. Oxford: Blackwell Publishers. [4] Reynolds, J. H., Chelazzi, L., & Desimone, R. (1999). Competitive mechanisms subserve attention in macaque areas V2 and V4. *The Journal of Neuroscice*, *19*, 1736-1753. [5] Kastner, S., De Weerd, P., Desimone, R., & Ungerleider, L. G. (1998). Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI. *Science*, *282*, 108-111. [6] Corbetta, M., Miezin, F. M., Shulman, G. L., & Petersen, S. E. (1993). A PET study of visuospatial attention. *The Journal of Neuroscience*, *13*, 1202-1226. [7] Taylor, P. C., Nobre, A. C., & Rushworth, M. F. (2006). FEF TMS affects visual cortical activity. *Cerebral Cortex*, *17*, 391-399. [8] Grent-'t-Jong, T., & Woldorff, M. G. (2007). Timing and Sequence of Brain Activity in Top-Down Control of Visual-Spatial Attention. *PLoS Biology*, *5*, e12. [9] Ramachandran, V. S., & Cobb, S. (1995). Visual attention modulates metacontrast masking. *Nature*, *373*, 66-68. [10] Ress, D., Backus, B. T., & Heeger, D. J. (2000). Activity in primary visual cortex predicts performance in a visual detection task.* **Nature Neuroscience*, *3*, 940-945. |